PRICKLE1 antibody

Catalog No. ABIN7117768

This Rabbit Polyclonal antibody specifically detects PRICKLE1 in WB, ELISA and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for PRICKLE1 antibody (ABIN7117768)

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRICKLE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-PRICKLE1 Antibody

Purpose: PRICKLE1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: prickle homolog 1(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PRICKLE1

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Alternative Name: PRICKLE1

Background:

Synonyms: Prickle-like protein 1|REST/NRSF-interacting LIM domain protein 1|PRICKLE1|RILP

Background: Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

Molecular Weight: 94 kDa, 55-60 kDa

Gene ID: 144165

UniProt: Q96MT3

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus